IF007
Interferon-α A Protein, Recombinant human
Purified Recombinant Human Interferon Alpha A (Hu-IFN-alphaA & Hu-IFN-alpha2a).
Synonym(s):
Interferon alpha-2
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
Assay
95%
form
liquid
manufacturer/tradename
Chemicon®
technique(s)
cell culture | mammalian: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
Product Source: cDNA obtained from human leukocyte mRNA expressed in E. coli.
Purified Recombinant Human Interferon Alpha A (Hu-IFN-alphaA; Hu-IFN-alpha2a). Human Gene: IFNA2
Unit Definition
Specific Activity: The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-alphaA) provided by the National Institutes of Health.Unit of activity measured on bovine MDBK cells challenged with vesicular stomatitis virus (VSV).
Physical form
Frozen, in PBS containing 0.1% bovine serum albumin (BSA).
Storage and Stability
After receipt, this product should be kept at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Dilute only in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Analysis Note
Specific Activity: Determined by assaying inhibition of virus-induced cytopathic effect.In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells.
Yang, et al.
Cancer research communications, 3, 592-606 (2023)
Ming-Wei Jan et al.
Viruses, 14(7) (2022-07-28)
Human platelet lysate (hPL) contains abundant growth factors for inducing human cell proliferation and may be a suitable alternative to fetal bovine serum (FBS) as a culture medium supplement. However, the application of hPL in virological research remains blank. Parechovirus
Yang Liu et al.
Nature communications, 13(1), 4337-4337 (2022-07-28)
We report a live-attenuated SARS-CoV-2 vaccine candidate with (i) re-engineered viral transcription regulator sequences and (ii) deleted open-reading-frames (ORF) 3, 6, 7, and 8 (∆3678). The ∆3678 virus replicates about 7,500-fold lower than wild-type SARS-CoV-2 on primary human airway cultures
Heather M Froggatt et al.
Science signaling, 14(691) (2021-07-15)
The type I interferon (IFN) response is an important component of the innate immune response to viral infection. Precise control of IFN responses is critical because insufficient expression of IFN-stimulated genes (ISGs) can lead to a failure to restrict viral
Agata Sekrecka et al.
Cellular and molecular life sciences : CMLS, 80(7), 187-187 (2023-06-22)
To understand in detail the transcriptional and functional overlap of IFN-I- and IFN-II-activated responses, we used an integrative RNAseq-ChIPseq approach in Huh7.5 cells and characterized the genome-wide role of pSTAT1, pSTAT2, IRF9 and IRF1 in time-dependent ISG expression. For the
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service