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L050080

Sigma-Aldrich

Cap B

configured for PerkinElmer, configured for Polygen

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.21

type

for DNA synthesis

product line

Proligo Reagents

form

liquid

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)

color

clear

suitability

conforms to structure (GC, Formulation)

compatibility

configured for PerkinElmer
configured for Polygen

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General description

Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Preparation Note

Tetrahydrofurane / N-Methylimidazole / Pyridine 8/1/1 (v/v/v)

Other Notes

Cap B solution, containing tetrahydrofuran (THF), pyridine and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

6.1 °F

Flash Point(C)

-14.4 °C

Certificates of Analysis (COA)

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