200654
Ethyl cellulose
viscosity 300 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Synonym(s):
Ethylcellulose
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About This Item
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form
granular
autoignition temp.
698 °F
concentration
48.0-49.5%
extent of labeling
48% ethoxyl
refractive index
n20/D 1.47 (lit.)
viscosity
300 cP, 5 % in toluene/ethanol 80:20(lit.)
transition temp
softening point 157 °C
density
1.14 g/mL at 25 °C (lit.)
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General description
Ethyl cellulose (EC) is a non-toxic, biocompatible, and hydrophobic polymer used for the sustained release preparation of pharmaceutical products.
Application
Ethyl cellulose can be used to prepare polymer coatings for various applications. For example, it is used to encapsulate salt hydrates for low-temperature heat storage applications.
It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).
It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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The potential of excipient coating to enhance aerosol performance of micronized drugs in carrier excipient-drug blends, used in dry powder inhalers, was investigated. Both EC (ethyl cellulose) and PVP (polyvinylpyrrolidone) were used as coating agents. Carriers were prepared via sieve
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 240-248 (2012-11-20)
Films of ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC) can be used for extended release coatings in oral formulations. The permeability and microstructure of free EC/HPC films with 30% w/w HPC were studied to investigate effects of EC molecular
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The design and fabrication of sustained/controlled release dosage forms, employing new excipients capable of extending/controlling the release of drugs from the dosage forms over prolonged periods, has worked well in achieving optimally enhanced therapeutic levels of the drugs. In this
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