120685

N-Cyclohexylformamide

99%

• Linear Formula: HCONHC₆H₁₁
• CAS Number: 766-93-8
• Molecular Weight: 127.18
• MDL number: MFCD00003828
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847425
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• form: solid
• bp: 113 °C/700 mmHg (lit.)
• mp: 36-41 °C (lit.)
• functional group: amide
• SMILES string: O=CNC1CCCCC1
• InChI: 1S/C7H13NO/c9-6-8-7-4-2-1-3-5-7/h6-7H,1-5H2,(H,8,9)
• InChI key: SWGXDLRCJNEEGZ-UHFFFAOYSA-N
• Gene Information: human ... ADH1A(124) , ADH1B(125) , ADH1C(126) , ADH4(127) , ADH7(131) , EPHX2(2053) ; mouse ... Ephx2(13850)

Description

General description

N-Cyclohexylformamide binds to the complex of horse liver alcohol dehydrogenase with NADH and is similar to the Michaelis complex for aldehyde reduction catalyzed by the enzyme[1]. It is formed during hydration of cyclohexyl isocyanide catalyzed by a novel enzyme isonitrile hydratase from Pseudomonas putida N19-2 [2].

Application

N-Cyclohexylformamide was used in the synthesis of 2-methylidene-1,3-selenazolidine derivatives[3].

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318,H335
• Precautionary Statements: P261 - P280 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): >235.4 °F - closed cup
• Flash Point(C): > 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves