S0375

D-Saccharic acid 1,4-lactone monohydrate

≥98.0% (HPLC)

• Synonym(s): D-Glucaric acid-1,4-lactone, D-Saccharolactone
• Empirical Formula (Hill Notation): C₆H₈O₇ · H₂O
• CAS Number: 61278-30-6
• Molecular Weight: 210.14
• Beilstein: 85594
• MDL number: MFCD00149334
• UNSPSC Code: 12352201
• PubChem Substance ID: 24899420
• NACRES: NA.25

Properties

• Assay: ≥98.0% (HPLC)
• form: powder
• impurities: ≤10.0% water (Karl Fischer)
• color: white
• mp: 91 - 93 °C ((196 - 199 °F ))
• solubility: water: 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
• InChI: 1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
• InChI key: NPFKVZHSFSFLPU-QGBSHYGGSA-N

Description

General description

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).

Application

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves