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Key Documents

P4747

Sigma-Aldrich

Anti-Potassium Channel KCa2.3, (C-term) (Small-conductance Ca2+-activated Potassium Channel 3) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-SK3, Anti-SKCa3

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human, mouse, rat, pig

technique(s)

western blot: 1:200 using rat brain membranes

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNN3(3782)
mouse ... Kcnn3(140493)
rat ... Kcnn3(54263)

Immunogen

Synthetic peptide corresponding to amino acid residues 659-674 of human KCa2.3. This sequence has 100% homology in rat, mouse, pig.

Physical form

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Sang-Gyun Kang et al.
Cells, 12(14) (2023-07-29)
Prion diseases are progressive neurodegenerative disorders affecting humans and various mammals. The prominent neuropathological change in prion-affected brains is neuroinflammation, histopathologically characterized by reactive gliosis surrounding prion deposition. The cause and effect of these cellular responses are still unclear. Here
Shaun L Sandow et al.
Journal of anatomy, 209(5), 689-698 (2006-10-26)
Activation of endothelial cell small- (S) and intermediate- (I) conductance calcium-activated potassium channels (K(Ca)) and current or molecular transfer via myoendothelial gap junctions underlies endothelium-derived hyperpolarization leading to vasodilation. The mechanism underlying the K(Ca) component of vasodilator activity and the

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