Skip to Content
Merck
All Photos(1)

Documents

N4007

Sigma-Aldrich

N-Nitroso-N-methylbutylamine

Synonym(s):

Methylbutylnitrosamine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C5H12N2O
CAS Number:
7068-83-9
Molecular Weight:
116.16
MDL number:
MFCD00056645
UNSPSC Code:
12352116
PubChem Substance ID:
24897361
NACRES:
NA.25

form

liquid

Quality Level

200

density

0.93 g/mL (lit.)

storage temp.

2-8°C

SMILES string

CCCCN(C)N=O

InChI

1S/C5H12N2O/c1-3-4-5-7(2)6-8/h3-5H2,1-2H3

InChI key

PKTSCJXWLVREKX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Packaging

Bulk package

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H310 + H330,H350

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Carc. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

M Lee et al.
Cancer research, 49(6), 1470-1474 (1989-03-15)
Metabolic activation may be a key step in determining the tissue specificity of carcinogenic nitrosamines. In previous work, we characterized P450IIE1 (an acetone/ethanol-inducible form of cytochrome P-450) as the major enzyme for the metabolic activation of N-nitrosodimethylamine. In this work
K E Appel et al.
Carcinogenesis, 7(4), 659-663 (1986-04-01)
To demonstrate whether there are any pathways of nitrite formation from N-nitrosamines other than reductive denitrosation by cytochrome P-450 we performed the following experiments. An esterified alpha-hydroxylated nitrosamine was incubated in a microsomal system to test if nitrite generation is
J G Farrelly et al.
Cancer research, 42(6), 2105-2109 (1982-06-01)
With the use of rat liver preparations, the in vitro microsomal metabolism of methylethylnitrosamine, methyl-n-butylnitrosamine, and methyl(2-phenylethyl)nitrosamine labeled with deuterium in the methyl and alpha-methylene positions has been compared with that of the parent (unlabeled) compounds. All three forms of
P P Roller et al.
IARC scientific publications, (41)(41), 199-208 (1982-01-01)
Electron-impact mass spectra of N-nitrosomethyl-n-butylamine, 5 of its specifically deuterated anologs and its methyl-n-hexyl and methyl-n-octyl homologs have been examined. Hydrogen abstraction by the nitrosamino moiety dominates the rearrangement ions, especially at low ionization energy. All compounds exhibited the (M-OH)+
T Koreeda et al.
Anticancer research, 19(5B), 4139-4143 (2000-01-11)
The inhibitory effect of a synthetic retinoid, ethyl alltrans-9-(4-methoxy-2, 3, 6-trimethyl-phenyl)-3, 7-dimethyl-2, 4, 6, 8-nonatetraenoate (Tigason), on esophageal carcinogenesis in F344 rats induced by N-nitroso-N-methylbutylamine (NMBA) was evaluated. The animals were given NMBA daily in their drinking water for 21
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service