M046000

Cyanine 5 Phosphoramidite

• Synonym(s): 2-[5-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium
• Empirical Formula (Hill Notation): C₆₀H₇₂N₄O₄P
• CAS Number: 351186-76-0
• Molecular Weight: 944.21
• UNSPSC Code: 41116105

Properties

• product line: Proligo Reagents
• Assay: ≥90% (³¹P-NMR); ≥95.0% (reversed phase HPLC)
• drug control: USDEA Schedule I
• color: clear blue0.1M in Acetonitrile
• shipped in: dry ice; dry ice
• storage temp.: −20°C
• SMILES string: CC(C1=C(N/2CCCOP(N(C(C)C)C(C)C)OCCC#N)C=CC=C1)(C)C2=C\C=C\C=C\C(C3(C)C)=[N+](CCCOC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)C7=C3C=CC=C7.[Cl-]
• InChI: 1S/C60H72N4O4P.ClH/c1-46(2)64(47(3)4)69(67-44-23-40-61)68-45-25-42-63-55-33-22-20-31-53(55)59(7,8)57(63)35-18-12-17-34-56-58(5,6)52-30-19-21-32-54(52)62(56)41-24-43-66-60(48-26-13-10-14-27-48,49-28-15-11-16-29-49)50-36-38-51(65-9)39-37-50;/h10-22,26-39,46-47H,23-25,41-45H2,1-9H3;1H/q+1;/p-1
• InChI key: GWCNEDQILVVBDJ-UHFFFAOYSA-M

Description

General description

Phosphoramidite technology is ideally suited for the modification of synthetic oligonucleotides with covalently attached reporter moieties, linkers, spacers, or haptens. Sigma-Aldrich provides popular reporters and linkers ready to use for DNA/RNA synthesis machines. Cyanine 5 Phosphoramidite is one such label whose absorbance maxima is 646 nm and emission maxima is 662 nm.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable