Proceedings of the National Academy of Sciences of the United States of America, 111(34), E3534-E3543 (2014-08-13)
Remnants of ancient transposable elements (TEs) are abundant in mammalian genomes. These sequences harbor multiple regulatory motifs and hence are capable of influencing expression of host genes. In response to environmental changes, TEs are known to be released from epigenetic
In capillary zone electrophoresis the electrophoretic velocity of an ion decreases as the concentration of the background electrolyte solution is increased. This is caused by changes in the electrophoretic mobility of the ion (muep) as well as by changes in
A dynamic reaction cell ICP-MS was used as a CE detector for the speciation analysis of arsenic and selenium. Samples containing arsenite, arsenate, monomethylarsonic acid, dimethylarsinic acid, arsenobetaine, selenite, selenate, selenocysteine, selenomethione, and Se-methylselenocysteine were subjected to electrophoretic separation before
Critical care (London, England), 19, 278-278 (2015-07-15)
In severe respiratory and/or circulatory failure, extracorporeal membrane oxygenation (ECMO) may be a lifesaving procedure. Specialized departments provide ECMO, and these patients often have to be transferred for treatment. Conventional transportation is hazardous, and deaths have been described. Only a
The Journal of biological chemistry, 282(47), 34306-34314 (2007-09-26)
3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni catalyzes the oxidation of androsterone with NAD(+) to form androstanedione and NADH with a concomitant releasing of protons to bulk solvent. To probe the proton transfer during the enzyme reaction, we used mutagenesis, chemical
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