Skip to Content
Merck
All Photos(1)

Key Documents

C0279

Sigma-Aldrich

Carboxypeptidase Inhibitor from potato tuber

lyophilized powder

Sign Into View Organizational & Contract Pricing


About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

biological source

plant (white russett potato)

form

lyophilized powder

potency

1.1-6.0 nM Ki [CPB]
1.5-3.5 nM Ki [CPA]

mol wt

apparent mol wt 4.075-4.333 kDa

composition

Protein, ≥35% Lowry

solubility

water: soluble 5 mg/mL, clear

storage temp.

−20°C

Biochem/physiol Actions

Broad-spectrum inhibitor of carboxypeptidases of animal digestive-tract origin, but little or no activity against plant and microbial carboxypeptidases. However, recent results suggest it may play a part in resistance to microbial pathogens by preventing digestion of protein.

Packaging

Package size based on protein content

Unit Definition

One μg of inhibitor protein will inhibit the activity of ≥3 μg of carboxypeptidase A by 50% using hippuryl-L-phenylalanine as substrate at pH 7.5 at 25°C.

Physical form

Lyophilized powder containing traces of sodium citrate and sodium chloride; balance primarily non-protein components.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jarosław Króliczewski et al.
Scientific reports, 6, 34557-34557 (2016-10-05)
The cytochrome b
Purification and properties of a carboxypeptidase inhibitor from potatoes.
C A Ryan et al.
The Journal of biological chemistry, 249(17), 5495-5499 (1974-09-10)
David Thompson et al.
The Journal of biological chemistry, 284(37), 24891-24903 (2009-07-11)
We have identified, purified, and characterized three subcomplexes of PA700, the 19 S regulatory complex of the 26 S proteasome. These subcomplexes (denoted PS-1, PS-2, and PS-3) collectively account for all subunits present in purified PA700 but contain no overlapping
Huaqi Tang et al.
Biotechnology and bioengineering, 118(3), 1405-1410 (2020-11-27)
Lack of experimental human models hinders research on Lassa hemorrhagic fever and the development of treatment strategies. Here, we report the first chip-based model for Lassa hemorrhagic syndrome. The chip features a microvessel interfacing collagen network as a simple mimic

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service