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Key Documents

B4310

Sigma-Aldrich

BIM 23056

≥95% (HPLC), solid

Synonym(s):

D-Phe-Phe-Tyr-D-Trp-Lys-VaL-Phe-D-Nal-NH2 trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C71H82N11O9 · xC2HF3O2
Molecular Weight:
1233.48 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

solid

color

white

solubility

H2O: >1 mg/mL

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... SSTR5(6755)
mouse ... SSTR5(20609)
rat ... SSTR5(25354)

Amino Acid Sequence

Phe-Phe-Tyr-Trp-Lys-Val-Phe-Nal-NH2

Biochem/physiol Actions

Selective sst5 somatostatin receptor antagonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Caroline Nunn et al.
European journal of pharmacology, 436(3), 173-186 (2002-02-23)
Somatostatin (somatotropin release inhibiting factor, SRIF), exerts its effects via specific G protein coupled receptors of which five subtypes have been cloned (sst1-5). Recently, SRIF receptors have also been cloned from fish tissues. In this study, goldfish sst5 receptors (gfsst5)
G F Wilkinson et al.
British journal of pharmacology, 118(3), 445-447 (1996-06-01)
We have investigated the effects of somatostatin (SRIF) and the linear octapeptide BIM-23056 on changes in intracellular calcium ion concentration ([Ca2+]i) and on the formation of inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) in CHO-K1 cells transfected with the human recombinant SRIF sst5 receptor. SRIF
Daniel G Blackmore et al.
iScience, 24(11), 103275-103275 (2021-11-12)
Hippocampal function is critical for spatial and contextual learning, and its decline with age contributes to cognitive impairment. Exercise can improve hippocampal function, however, the amount of exercise and mechanisms mediating improvement remain largely unknown. Here, we show exercise reverses

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