Skip to Content
Merck
All Photos(1)

Documents

C1510000

Chlorhexidine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide]

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
CAS Number:
Molecular Weight:
505.45
Beilstein:
2826432
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

chlorhexidine

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

134-136 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

InChI key

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorhexidine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S Karki et al.
The Journal of hospital infection, 82(2), 71-84 (2012-08-15)
The topical use of chlorhexidine gluconate (CHG) is intended to reduce bacterial density on patients' skin. To assess the impact of body bath or skin cleansing with CHG-impregnated or CHG-saturated washcloths in preventing healthcare-associated infections and colonization. This systematic review
Rengin Attin et al.
Australian orthodontic journal, 29(1), 52-57 (2013-06-22)
The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in highlevel MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement. The subjects of this single-blinded clinical trial
Sissel Skovgaard et al.
The Journal of antimicrobial chemotherapy, 68(10), 2226-2233 (2013-06-07)
Chlorhexidine is used as a disinfectant to prevent surgical infections. Recently, studies have indicated that chlorhexidine usage has selected methicillin-resistant Staphylococcus aureus strains that are tolerant to chlorhexidine and that this may be related to the presence of the qacA/B-encoded
Richard Price et al.
BMJ (Clinical research ed.), 348, g2197-g2197 (2014-04-02)
To determine the effect on mortality of selective digestive decontamination, selective oropharyngeal decontamination, and topical oropharyngeal chlorhexidine in adult patients in general intensive care units and to compare these interventions with each other in a network meta-analysis. Systematic review, conventional
Dana Robaei et al.
Ophthalmology, 121(7), 1383-1388 (2014-03-19)
To examine the impact of topical corticosteroid use before the diagnosis of Acanthamoeba keratitis (AK) on final visual outcomes and to determine the prognostic factors predicting poorer outcomes. Cohort study. A total of 209 eyes of 196 patients with retrievable

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service