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EZRMGIP

Millipore

Rat/Mouse GIP ELISA Kit

measures and quantifies GIP levels in 10 μL serum, plasma or cell culture supernatent

Synonym(s):

Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Incretin hormone

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Rat/Mouse GIP (total) ELISA, This Rat/Mouse GIP (total) ELISA is used to measure & quantify GIP levels in Metabolism & Endocrine research.

Quality Level

200

species reactivity

mouse, rat

packaging

kit of 1 × 96 wells

parameter

10 μL sample volume (4hr assay)

assay range

accuracy: 104.2%
linearity: 100.8%
sensitivity: 8.2 pg/mL
standard curve range: 8.2-2000 pg/mL

technique(s)

ELISA: suitable

input

sample type cell culture supernatant
sample type plasma (K2 EDTA)
sample type serum

UniProt accession no.

P48756
Q06145

application(s)

research use

detection method

colorimetric (450nm/590nm)

shipped in

wet ice

storage temp.

2-8°C

General description

Gastric inhibitory peptide (GIP) or the glucose-dependent insulinotropic polypeptide is a gastrointestinal peptide hormone and belongs to the glucagon superfamily. It is released after the absorption of glucose or fat by the duodenal endocrine K cells. GIP is involved in glucose-induced insulin secretion. This Rat/Mouse GIP (total) ELISA is used to quantify GIP levels in metabolism and endocrine research.

Application

Rat/Mouse GIP (total) ELISA has been used to measure the levels of total GIP in rat plasma and serum samples.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificates of Analysis (COA)

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K Miyawaki et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(26), 14843-14847 (1999-12-28)
Mice with a targeted mutation of the gastric inhibitory polypeptide (GIP) receptor gene (GIPR) were generated to determine the role of GIP as a mediator of signals from the gut to pancreatic beta cells. GIPR-/- mice have higher blood glucose
Fumie Ikezawa et al.
Surgery, 151(6), 822-830 (2012-02-10)
Ileal interposition (IT), in which the distal ileum is transposed isoperistaltically into the proximal jejunum, is considered as a procedure for metabolic or antidiabetes surgery. Our aim was to study the effects of IT on glycemic control, fat metabolism, and
N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119.
Zhi-Liang Chu,Chris Carroll,Ruoping Chen,Jean Alfonso,Veronica Gutierrez,Hongmei He et al.
Molecular Endocrinology null
N Inagaki et al.
Molecular endocrinology (Baltimore, Md.), 3(6), 1014-1021 (1989-06-01)
Gastric inhibitory polypeptide (GIP) is a 42-amino-acid hormone which may have a role in the regulation of insulin secretion. The characterization of cDNA clones encoding this hormone indicates that it is derived by proteolytic processing of a 153-amino-acid precursor. The
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.
Sara Edfalk, Par Steneberg, Helena Edlund
Diabetes null
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