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233483

Sigma-Aldrich

Coagulation Factor XIa, Human Plasma

Coagulation Factor XIa, Human Plasma, is a native coagulation factor XIa prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation.

Synonym(s):

Coagulation Factor

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.25

Quality Level

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Native coagulation factor XIa from human plasma prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation. In vivo, Factor XI is activated to Factor XIa via Factor XIIa and High Molecular Weight Kininogen (Cat. No. 422686). Factor XIa activates Factor IX to Factor IXa in a reaction that does not require membrane surfaces.
Native coagulation factor XIa from human plasma prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation. In vivo, Factor XI is activated to Factor XIa via Factor XIIa and High Molecular Weight Kininogen (Cat. No. 422686). Factor XIa activates Factor IX to Factor IXa in a reaction that does not require membrane surfaces.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

homogeneous by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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