Skip to Content
Merck
All Photos(1)

Documents

A-913

Supelco

7-Aminonitrazepam solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C15H13N3O
CAS Number:
4928-02-3
Molecular Weight:
251.28
EC Number:
200-835-2
MDL number:
MFCD00800998
UNSPSC Code:
41116107
PubChem Substance ID:
329771036
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

O=C1NC2=CC=C(N)C=C2C(C3=CC=CC=C3)=NC1

InChI

1S/C15H13N3O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9,16H2,(H,18,19)

InChI key

OYOUQHVDCKOOAL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

7-Aminonitrazepam is a major urinary metabolite of nitrazepam, a benzodiazepine used to treat insomnia and sold under the trade names Mogadon and Alodorm. This certified solution standard is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug monitoring of nitrazepam use.

Application

<ul>
<li><strong>7-Aminonitrazepam in forensic toxicology:</strong> 7-Aminonitrazepam is used as an analytical reference in the evaluation of hyperlipidemic postmortem blood, demonstrating its importance in forensic settings for accurate drug profiling (Elenst&aring;l et al., 2023).</li>
</ul>

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S Takeno et al.
Toxicology and applied pharmacology, 121(2), 233-238 (1993-08-01)
This study was designed to evaluate the developmental toxicity of nitrazepam (NZ) in Sprague-Dawley rats and ICR mice and to determine the metabolic factors which modulate susceptibility to the developmental effects of NZ. Rats were treated orally with a single
B J Hart et al.
Methods and findings in experimental and clinical pharmacology, 10(1), 21-26 (1988-01-01)
The stability of some selected benzodiazepines in saliva has been studied. The benzodiazepines nitrazepam and clonazepam were found to be unstable in saliva at room temperature and nitrazepam was converted into 7-aminonitrazepam. The conversion rate of nitrazepam was strongly dependent
Yu Zhu et al.
Se pu = Chinese journal of chromatography, 20(5), 394-397 (2005-12-20)
A highly sensitive method has been developed for the analysis of 7-aminonitrazepam (7-ANIZ), the major metabolite of nitrazepam, in urine by trimethylsilyl derivatization-gas chromatography/mass spectrometry. Urine samples were extracted with ethyl ether-ethyl acetate (99:1, volume ratio). The extracts were derivatized
High-performance liquid chromatographic determination of nitrazepam and its metabolites in human urine.
T Kozu
Journal of chromatography, 310(1), 213-218 (1984-09-14)
M Tomita et al.
Journal of chromatography, 621(2), 249-255 (1993-11-24)
We applied micellar electrokinetic capillary chromatography to simultaneous separation and determination of nitrazepam and its major metabolites, 7-aminonitrazepam and 7-acetamidonitrazepam, in spiked urine. Prior to electrophoresis, the three compounds were successfully extracted from the spiked urine with commercial disposable solid-phase
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service