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B4638

Sigma-Aldrich

Betahistine dihydrochloride

≥98%

Synonym(s):

Methyl[2-(2-pyridyl)ethyl]amine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H12N2 · 2HCl
CAS Number:
5579-84-0
Molecular Weight:
209.12
EC Number:
226-966-5
MDL number:
MFCD00012813
UNSPSC Code:
12352100
PubChem Substance ID:
57653935
NACRES:
NA.22

Quality Level

100

Assay

≥98%

form

powder

SMILES string

Cl.CNCCc1ccccn1

InChI

1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H

InChI key

XVDFMHARQUBJRE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269) , HRH3(11255)

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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2-Vinylpyridine 97%

Sigma-Aldrich

132292

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Betahistine hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1065618

Betahistine hydrochloride

Franziska Lezius et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 268(8), 1237-1240 (2011-06-01)
The objective of this study was to evaluate the clinical benefit and the side effects of high dosages of betahistine dihydrochloride (288-480 mg/day) in patients with severe Menière's disease (MD). In this case series 11 patients with MD who had
T Y Kew et al.
The Journal of laryngology and otology, 126(1), 66-71 (2011-08-27)
We report an extremely rare case of duplication of the internal auditory canal associated with dysfunction of both the facial and vestibulocochlear nerves. We also review the literature regarding the integrity of the facial and vestibulocochlear nerves in such cases.
Maurício Malavasi Ganança et al.
Brazilian journal of otorhinolaryngology, 77(4), 499-503 (2011-08-24)
Betahistine is a medicine used to treat vestibular disorders that has also been used to treat tinnitus. To assess the effects of betahistine on tinnitus in patients with vestibular disorders. Retrospective data were collected from patient records for individuals presenting
Burkhard Franz et al.
Acta oto-laryngologica, 131(11), 1155-1159 (2011-09-13)
Betahistine dihydrochloride, a drug used widely in the systemic treatment of balance disorders such as Ménière's disease, was found to improve eustachian tube function when applied topically in the nasopharynx of rats. The study tested the effect of betahistine, a
Enis Alpin Guneri et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 146(1), 104-108 (2011-08-20)
The purpose of this study is to evaluate the effects of betahistine in addition to Epley maneuver on the quality of life of patients with posterior semicircular canal benign paroxysmal positional vertigo (BPPV) of the canalithiasis type. Double-blind, randomized, controlled
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