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Key Documents

902934

Sigma-Aldrich

Allyl-poly(ethylene glycol)

average Mn 5,000, PDI <1.3

Synonym(s):

Allyl-PEG-OH, PEG 5k, PEG allyl, Polyethylene glycol

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About This Item

Linear Formula:
C3H5(C2H4O)nOH
MDL number:
UNSPSC Code:
12352112
NACRES:
NA.23

form

powder or solid

mol wt

PEG ~5,000 Da
average Mn 5,000

color

off-white to pale yellow

PDI

<1.3

storage temp.

2-8°C

General description

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

Application

This heterobifunctional PEG has an allyl functionality on one end and an alcohol on the other. The allyl is commonly used in thiol-ene click chemistry; as well as other ligation reactions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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