I3275

Interferon-γ from rat

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinônimo(s): IFN-γ
• Número MDL: MFCD00283531
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: rat
• Nível de qualidade: 200
• recombinante: expressed in E. coli
• Ensaio: ≥97% (SDS-PAGE)
• forma: lyophilized powder
• peso molecular: 15.5 kDa
• embalagem: pkg of 0.1 mg
• técnica(s): cell culture | mammalian: suitable
• Impurezas: endotoxin, tested
• cor: white
• nº de adesão UniProt: P01581
• temperatura de armazenamento: −20°C
• Informações sobre genes: rat ... Ifng(25712)

Descrição

Aplicação

Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.

Ações bioquímicas/fisiológicas

Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.

Características e benefícios

The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.

forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)