F2802

Fluvoxamine maleate

neuronal serotonin reuptake inhibitor, solid

• Sinônimo(s): (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
• Fórmula empírica (Notação de Hill): C₁₅H₂₁F₃N₂O₂ · C₄H₄O₄
• Número CAS: 61718-82-9
• Peso molecular: 434.41
• UNSPSC Code: 12352116
• PubChem Substance ID: 24278162
• NACRES: NA.77
• MDL number: MFCD00269809
• Form: solid

Propriedades

• Nome do produto: Fluvoxamine maleate, solid
• form: solid
• Quality Segment: 200
• solubility: H₂O: soluble
• originator: Solvay
• storage temp.: 2-8°C
• SMILES string: COCCCC/C(C1=CC=C(C(F)(F)F)C=C1)=N\OCCN.OC(/C=C\C(O)=O)=O
• InChI: 1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
• InChI key: LFMYNZPAVPMEGP-PIDGMYBPSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC6A4(6532) ;

Descrição

Application

Fluvoxamine maleate has been used as a test compound to determine the solubility and effective blood-brain barrier permeability.(2)

Biochem/physiol Actions

Fluvoxamine maleate is a selective neuronal serotonin reuptake inhibitor. It functions as an antidepressant and anti-obsessive agent. It is useful in treating obsessive compulsive disorder and panic disorder.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Solvay. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações de segurança

• Pictogramas: GHS07
• Palavra de aviso: Warning
• Códigos de risco: H302,H315
• Classe de armazenamento: 11 - Combustible Solids
• Ponto de inflamação (°F): Not applicable
• Ponto de inflamação (°C): Not applicable
• EPI (equipamento de proteção individual): dust mask type N95 (US), Eyeshields, Gloves
• Declarações de precaução: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Oral - Skin Irrit. 2