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Merck

HRH1

histamine receptor H1

Sinônimos:
H1-R, hisH1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • naked mole-rat(101715481) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • cow(281231) histamine receptor H1
  • dog(403813) histamine receptor H1
  • Zebrafish(735302) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Histamine dihydrochloride, ≥99.0% (AT),
Espécies
human
Histamine, analytical standard,
Espécies
human
Histamine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Histamine, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Histamine dihydrochloride, ≥99% (TLC), powder,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Diphenhydramine hydrochloride, ≥98% (HPLC),
Espécies
human
Promethazine hydrochloride, ,
Espécies
human
Cetirizine dihydrochloride, ≥98% (HPLC),
Espécies
human
Astemizole, ≥98% (HPLC),
Espécies
human
Clemastine fumarate salt, ≥98% (HPLC),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Reatividade de espécies
bovine, mouse, rat
Aplicação
ELISA
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Cinnarizine, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Cinnarizine, powder,
Espécies
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Espécies
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Ketotifen fumarate salt, ,
Espécies
human
L-Histidinol dihydrochloride, ≥98 (TLC),
Espécies
mouse, rat, human
D-Histidine monohydrochloride monohydrate, ≥98% (TLC),
Espécies
mouse, rat, human
Loratadine, ≥98% (HPLC), powder,
Espécies
rat, human
Histamine, ≥97.0%,
Espécies
human, rat

Small Molecule - Ligand

Número do produto
Descrição
Espécies
Loratadine, ≥98% (HPLC), powder,
Espécies
rat, human
Cinnarizine, powder,
Espécies
human

Small Molecule - Metabolite

Número do produto
Descrição
Espécies
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Espécies
human

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
2-(2-Pyridyl)ethylamine, 95%,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Hrh1,
Espécies
mouse
MISSION® esiRNA, targeting human HRH1,
Espécies
human