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V1258

Sigma-Aldrich

[Arg8]-Vasotocin-Gly-Lys-Arg

≥97% (HPLC)

Synonym(s):

Hydrin I

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About This Item

Empirical Formula (Hill Notation):
C57H93N21O16S2
CAS Number:
122842-47-1
Molecular Weight:
1392.61
MDL number:
MFCD00076729
UNSPSC Code:
12352200
PubChem Substance ID:
24900714

Product Name

[Arg8]-Vasotocin-Gly-Lys-Arg, ≥97% (HPLC)

Assay

≥97% (HPLC)

UniProt accession no.

P01185

storage temp.

−20°C

SMILES string

CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C57H93N21O16S2/c1-3-29(2)45-53(91)72-35(17-18-41(60)80)49(87)75-38(24-42(61)81)50(88)76-39(28-96-95-27-32(59)46(84)74-37(51(89)77-45)23-30-13-15-31(79)16-14-30)54(92)78-22-8-12-40(78)52(90)71-33(10-6-20-66-56(62)63)47(85)69-25-43(82)68-26-44(83)70-34(9-4-5-19-58)48(86)73-36(55(93)94)11-7-21-67-57(64)65/h13-16,29,32-40,45,79H,3-12,17-28,58-59H2,1-2H3,(H2,60,80)(H2,61,81)(H,68,82)(H,69,85)(H,70,83)(H,71,90)(H,72,91)(H,73,86)(H,74,84)(H,75,87)(H,76,88)(H,77,89)(H,93,94)(H4,62,63,66)(H4,64,65,67)

InChI key

BJRAYGWQMPNTHC-UHFFFAOYSA-N

Gene Information

human ... AVP(551)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
014H08931

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R Acher et al.
Biology of the cell, 89(5-6), 283-291 (1997-08-01)
Volemia and osmolality homeostasis is ensured in vertebrates through neuroendocrine reflexes, involving an afferent neural branch from baro- and osmo-receptors to hypothalamus and an efferent endocrine branch from secretory neurons to target hydroosmotic cells equipped with receptors and effectors. Whereas
P Eggena et al.
The American journal of physiology, 259(4 Pt 1), E524-E528 (1990-10-01)
Hydrin 1 is the biosynthetic precursor of vasotocin in Xenopus laevis. We have synthesized deamino and fluorescein analogues of hydrin 1 and characterized their physiological action in the urinary bladder of the toad, Bufo marinus. 1-Deamino-hydrin 1 (d-hydrin) was more
J T Winslow et al.
European journal of pharmacology, 233(1), 101-107 (1993-03-16)
The neurohypophyseal peptide hormone arginine-vasopressin functions as a neuropeptide in several brain areas in addition to its role as a posterior pituitary hormone. Several studies indicate that arginine-vasopressin and arginine-vasopressin receptors appear early in the infant rat brain. To determine
Y Rouillé et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(14), 5272-5275 (1989-07-01)
From neurointermediate pituitary glands of Xenopus laevis and Rana esculenta, previously unreported peptides termed hydrins, active on water permeability of frog urinary bladder and frog skin (Brunn or "water-balance" effect), have been isolated and sequenced. These peptides seem to be
S Iwamuro et al.
Biochimica et biophysica acta, 1176(1-2), 143-147 (1993-03-10)
The neurohypophysis of Xenopus and that of Ranidae and Bufonidae contain hydrin 1 (vasotocinyl-Gly-Lys-Arg) and hydrin 2 (vasotocinyl-Gly), respectively. In order to test the aldosterone-releasing activity of arginine vasotocin (AVT) and hydrin 1, purification of these peptides from an acid-extract
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