SRP4248

MIP-1beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonym(s): CCL4, MIP-1- β, Macrophage inflammatory protein 1-β, Small inducible cytokine A4, T-cell activation protein 2
• MDL number: MFCD00213006
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: mouse
• recombinant: expressed in E. coli
• Assay: ≥98% (HPLC); ≥98% (SDS-PAGE)
• form: lyophilized
• mol wt: ~7.8 kDa
• packaging: pkg of 10 μg
• impurities: endotoxin, tested
• NCBI accession no.: P14097
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Ccl4(20303)

Description

General description

Mouse macrophage inflammatory protein-1β (MIP-1β) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.
MIP-1β is mainly generated by monocytes and lymphocytes. It is a member of CC family of chemokine intercrine cytokine. MIP-1β shares 70% similarity with MIP-1α. It is localized to a number of tissues such as smooth muscles, monocytes, neutrophils, mast cells, fibroblast B and T lymphocytes.[1]

Biochem/physiol Actions

Macrophage inflammatory protein-1 β (MIP-1β) promotes myelopoietic cellular growth and induces leukocyte chemoattraction. MIP-1β is an effective HIV infection suppressor.[1]

Physical form

Lyophilized without any additives.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.