SML1059

MMB-4

≥98% (HPLC)

• Synonym(s): 1,1′-Methylenebis[4-[(hydroxyimino)methyl]-pyridinium dibromide
• Empirical Formula (Hill Notation): C₁₃H₁₄N₄O₂ · 2Br
• CAS Number: 2058-89-1
• Molecular Weight: 418.08
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825642
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: light yellow to light brown
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O/N=C/C1=CC=[N+](C[N+]2=CC=C(/C=N\O)C=C2)C=C1.[Br-].[Br-]
• InChI: 1S/C13H12N4O2.2BrH/c18-14-9-12-1-5-16(6-2-12)11-17-7-3-13(4-8-17)10-15-19;;/h1-10H,11H2;2*1H
• InChI key: ZKQNRRLCBJUEBC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MMB-4 is also called as 1,1′-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride. It serves as a promising antidote for organophosphate poisoning.

MMB-4 is an oxime that can reactivate cholinesterases that have been inactivated by exposure to organophosphates such as sarin or soman. Administration of MMB-4 and atropine normalizes many respiratory parameters in guinea pigs following soman inhalation.

Features and Benefits

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Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable