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S5187

Sigma-Aldrich

Monoclonal Anti-SNAP-25 antibody produced in mouse

clone SP12, purified immunoglobulin, buffered aqueous solution

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About This Item

MDL number:
MFCD00675279
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

SP12, monoclonal

form

buffered aqueous solution

species reactivity

pig, hamster, rat, human

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

P60880

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SNAP25(6616)
rat ... Snap25(25012)

Immunogen

crude human synaptic precipitate.

Physical form

Solution in phosphate buffered saline containing 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Certificates of Analysis (COA)

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Katsusuke Hata et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(52), 14481-14493 (2007-12-28)
Characterization of neuromuscular junction formation and function in mice lacking all neural cell adhesion molecule (NCAM) isoforms or only the 180 isoform demonstrated that the 180 isoform was required at adult synapses to maintain effective transmission with repetitive stimulation whereas
Rosane Aparecida Ribeiro et al.
Experimental physiology, 97(9), 1065-1073 (2012-05-01)
Ageing is associated with an increased impairment in glucose homeostasis and an increased incidence of type 2 diabetes. In this study, we evaluated β-cell function and its implications for glucose homeostasis in 24-month-old female Wistar rats. Aged rats showed lower plasma
Aysegul Ilhan et al.
Molecular and cellular endocrinology, 298(1-2), 1-10 (2008-11-18)
This study was performed on the basis of previously obtained investigative gene array data concerning the over-expression of CXCL12/SDF-1 in human insulinomas versus human pancreatic islet preparations. The presence of CXCL12/SDF-1 was studied by RT-qPCR in human insulinomas (n=8) versus
Mário Ribeiro et al.
Journal of magnetic resonance imaging : JMRI (2018-01-30)
Type-2 diabetes mellitus (T2DM) is a metabolic disorder with a broad range of complications in the brain that depend on the conditions that precede its onset, such as obesity and metabolic syndromes. It has been suggested that neurotransmitter and metabolic
Sónia C Correia et al.
International journal of molecular sciences, 22(1) (2021-01-21)
The lack of effective disease-modifying therapeutics to tackle Alzheimer's disease (AD) is unsettling considering the actual prevalence of this devastating neurodegenerative disorder worldwide. Intermittent hypoxic conditioning (IHC) is a powerful non-pharmacological procedure known to enhance brain resilience. In this context
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