P148

4α-Phorbol 12-myristate 13-acetate

solid, ≥95% (TLC)

• Synonym(s): 4α-PMA
• Empirical Formula (Hill Notation): C₃₆H₅₆O₈
• CAS Number: 63597-44-4
• Molecular Weight: 616.83
• MDL number: MFCD00153860
• UNSPSC Code: 12352211
• PubChem Substance ID: 24898203
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (TLC)
• form: solid
• color: white
• solubility: H₂O: ~2 μM; DMSO: soluble; ethanol: soluble
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@]3(O)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(C)=O
• InChI: 1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34+,35-,36-/m1/s1
• InChI key: PHEDXBVPIONUQT-LQLWEASQSA-N

Description

General description

Though having aqueous solubility, it is recommended that this compound first be dissolved in a water miscible organic solvent before dilution to working concentrations in aqueous media.

Biochem/physiol Actions

Negative control for phorbol ester activation of protein kinase C.

Packaging

Sealed glass ampule.

Caution

Photosensitive

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves