This product is a mixture of Oleic acid and Cyclodextrin. Each gram of powder will include a minimum of 28 mg Oleic acid. The product is sold by Oleic acid content. At the minimum Oleic acid content, the 10 mg package size would contain a total of 357 mg of powder. The Oleic acid content is lot specific. Please see the link below to review a sample or lot specific Certificate of Analysis:
https://www.sigmaaldrich.com/product/sigma/o1257#product-documentation
O1257
Oleic Acid-Water Soluble
powder, BioReagent, suitable for cell culture
Synonym(s):
Oleic Acid–Cyclodextrin Complex
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10 MG
R$706.00
About This Item
biological source
synthetic (organic)
product line
BioReagent
form
powder
composition
Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL, clear to slightly hazy
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Gene Information
human ... SOAT1(6646) , SOAT2(8435)
Related Categories
Application
Oleic Acid-Water Soluble has been used:
- to prepare the FFAs (free fatty acids) mixture for cell treatment[1]
- to investigate its effect on the solute carrier family 2 member 4 (SLC2A4)/GLUT4 expression in L6 muscle cells and as potential transcriptional regulators[2]
- in the preparation of fatting media for the induction of in vitro steatosis in primary human hepatocytes[3]
Other Notes
Methyl-β-cylodextran binding improves the solubility and delivery of Oleic acid in culture media.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Certificates of Analysis (COA)
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Articles
Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.
How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.
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Could you please clarify whether the entire 10mg of the compound is oleic acid, or does the 10mg compound actually contain 377ug (37.7mg/g * 10mg) of oleic acid, considering the specified concentration?
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