MAK184
Succinate Colorimetric Assay Kit
Sufficient for 100 Colorimetric tests
Synonym(s):
Succinic Acid Assay Kit
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About This Item
Recommended Products
application(s)
cosmetics
food and beverages
detection method
colorimetric
relevant disease(s)
cardiovascular diseases; immunological diseases
storage temp.
−20°C
General description
Succinate (succinic acid) is a citric acid cycle intermediate and functions in the transport of electrons to the mitochondrial electron transport chain. It also functions in innate immune signaling and induces IL-1β production during inflammation. Succinates have been often used for the treatment of hypertension. Succinate measurements can be useful for studying its metabolic, immunological, and therapeutic activities.
Application
Succinate Colorimetric Assay Kit has been used to measure the concentration of succinate.
Suitability
Suitable for the detection of succinate in a variety of samples such as cell and tissue culture supernatants and in liquid samples such as wine.
Principle
The Succinate Colorimetric Assay Kit is a highly sensitive assay for determining succinate levels (ranging from 2-10 nmole/well) in a variety of samples. Succinate concentration is determined by a coupled enzyme reaction, which results in a colorimetric (450 nm) product proportional to the succinate present.
Kit Components Only
Product No.
Description
- Succinate Assay Buffer
- Succinate Converter
- Succinate Enzyme Mix
- Succinate Substrate Mix
- Succinate Developer
- Succinate Standard
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
Certificates of Analysis (COA)
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Metoprolol succinate extended release/hydrochlorothiazide combination tablets.
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Vascular Health, 3(3), 279-279 (2007)
Kimberly L Cramer-Morales et al.
Journal of Experimental Pathology, 1(2), 60-70 (2021-02-16)
Previous studies showed that human cell line HEK293 lacking mitochondrial superoxide dismutase (MnSOD) exhibited decreased succinate dehydrogenase (SDH) activity, and mice lacking MnSOD displayed significant reductions in SDH and aconitase activities. Since MnSOD has significant effects on SDH activity, and
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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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