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I9281

Sigma-Aldrich

5′-Iodoresiniferatoxin

solid

Synonym(s):

6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-daphnetoxin,20-(4-hydroxy-5-iodo-3-methoxybenzeneacetate), I-RTX

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About This Item

Empirical Formula (Hill Notation):
C37H39IO9
Molecular Weight:
754.60
MDL number:
MFCD09971003
UNSPSC Code:
12352200
PubChem Substance ID:
24896153

form

solid

color

white

solubility

DMSO: soluble 10 mg/mL

storage temp.

−20°C

SMILES string

COc1cc(CC(=O)OCC2=CC3C4OC6(Cc5ccccc5)O[C@]4(C[C@@H](C)[C@]3(O6)C7C=C(C)C(=O)[C@@]7(O)C2)C(C)=C)cc(I)c1O

InChI

1S/C37H39IO9/c1-20(2)35-16-22(4)37-26(33(35)45-36(46-35,47-37)18-23-9-7-6-8-10-23)12-25(17-34(42)29(37)11-21(3)32(34)41)19-44-30(39)15-24-13-27(38)31(40)28(14-24)43-5/h6-14,22,26,29,33,40,42H,1,15-19H2,2-5H3/t22-,26+,29-,33-,34-,35-,36?,37-/m1/s1

InChI key

TZUJORCXGLGWDV-RYACRXIZSA-N

Biochem/physiol Actions

Vanilloid receptor antagonist.

Legal Information

Sold in France, Germany, Great Britain and Switzerland under a patent license, restricted to research use only, from Procyon Pharmaceuticals, Inc.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nirlipta Swain et al.
Frontiers in cell and developmental biology, 10, 867057-867057 (2022-10-11)
Bi-directional crosstalk between Ca2+ signaling and ROS modulates physiological processes as a part of a regulatory circuit including sperm function. The role of transient receptor potential vanilloid 1 (TRPV1) in this regard cannot be undermined. This is the first report

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