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H7750

Sigma-Aldrich

DL-Histidine

≥99% (TLC), suitable for ligand binding assays

Synonym(s):

(±)-2-Amino-3-(4-imidazolyl)propionic acid

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
4998-57-6
Molecular Weight:
155.15
Beilstein:
7800
EC Number:
225-660-9
MDL number:
MFCD00005208
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24895803
NACRES:
NA.26

product name

DL-Histidine, ≥99% (TLC)

Assay

≥99% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

mp

273 °C (dec.) (lit.)

solubility

0.5 M HCl: soluble

application(s)

peptide synthesis

SMILES string

NC(Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)

InChI key

HNDVDQJCIGZPNO-UHFFFAOYSA-N

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Application

DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis.

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fouling behaviour of polyethersulfone UF membranes made with different PVP
J.Marchese
Journal of Membrane Science , 211, 1-11 (2009)
Worapan Pormsila et al.
Electrophoresis, 32(8), 884-889 (2011-03-12)
The quantification of plasma lactate and evaluation of the lactate threshold by CE with capacitively coupled contactless conductivity is demonstrated. The only sample preparation needed was deproteinization with a ACN/methanol mixture. A solution of 10 mmol/L 2-morpholinoethanesulfonic acid monohydrate, 10
Yoshikazu Tsukasaki et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(45), 16011-16016 (2014-10-31)
The cadherins Fat and Dachsous regulate cell polarity and proliferation via their heterophilic interactions at intercellular junctions. Their ectodomains are unusually large because of repetitive extracellular cadherin (EC) domains, which raises the question of how they fit in regular intercellular
Ana E Zeraik et al.
International journal for parasitology, 44(8), 523-531 (2014-04-29)
Septins are guanosine-5'-triphosphate-binding proteins involved in wide-ranging cellular processes including cytokinesis, vesicle trafficking, membrane remodelling and scaffolds, and with diverse binding partners. Precise roles for these structural proteins in most processes often remain elusive. Identification of small molecules that inhibit
Hai Zhou et al.
Nature communications, 5, 4884-4884 (2014-09-12)
Thermosensitive genic male-sterile (TGMS) lines, which are male-sterile at restrictive (high) temperatures but male-fertile at permissive (low) temperatures, have been widely used in breeding two-line hybrid rice (Oryza sativa L.). Here we find that mutation of thermosensitive genic male sterile
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