F7926
Anti-phospho-FAK (pTyr397) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
Synonym(s):
Anti-phospho-Focal Adhesion Kinase
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
MDL number:
UNSPSC Code:
12352203
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
usage
sufficient for 10 blots
species reactivity
human, rat, mouse, Drosophila, frog
technique(s)
western blot: 1:1,000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PTK2(5747)
General description
Focal adhesion kinase (FAK) is a cytoplasmic protein that belongs to non-receptor protein tyrosine kinase family. It has a critical role in regulation of cell differentiation, migration, adhesion and acceleration of the G1 to S phase transition in cell cycle. Anti-phospho-FAK (pTyr397) antibody can be used in immunocytochemistry and immunohistochemistry. Rabbit anti- phospho-FAK (pTyr397) antibody reacts specifically with FAK (125kD) phosphorylated at tyrosine 397. This product can also react with FAK (pTyr397) of rat, chicken, frog, mouse and human.
Immunogen
synthetic phophopeptide derived from the region of FAK that contains tyrosine 397.
Application
Anti-phospho-FAK (pTyr397) antibody can be used in immunoblotting (diluted 1:1000) and microarray.
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
J M Taylor et al.
The Journal of biological chemistry, 275(25), 19250-19257 (2000-04-06)
A variety of agonists including phenylephrine (PE) induce hypertrophy in neonatal ventricular cardiomyocytes. Here we report that signals provided by extracellular matrix proteins (ECM) augment the PE-induced hypertrophic response of cardiomyocytes and provide evidence that ECM-dependent signaling is mediated in
Xuelian Tang et al.
Cancer biology & therapy, 5(11), 1474-1480 (2006-10-03)
Herein, we report that marine-derived sulfated polysaccharide (MSP), a new kind of polysaccharide extracted from brown alga, exhibits the anti-migration effect in vitro and potently suppress metastasis of Lewis lung carcinoma in vivo. Adhesion assays demonstrated that MSP inhibits the
Sean E Gill et al.
Developmental biology, 298(2), 540-554 (2006-08-08)
Tissue inhibitors of metalloproteinases (TIMPs) regulate extracellular matrix (ECM) degradation by matrix metalloproteinases (MMPs) throughout embryogenesis. We examined lungs from TIMP3 null mice and found decreased bronchiole branching, enhanced activity of MMPs and enhanced fibronectin degradation throughout lung development compared
Potential roles for focal adhesion kinase in development.
Ridyard MS, Sanders EJ
Anat. Embryol., 199(1), 1-7 (1999)
Michelle L Chadwick et al.
Oncotarget, 9(37), 24750-24765 (2018-06-07)
Angiosarcoma is an aggressive malignancy of vascular origin that occurs de novo or in the context of previous cancer therapy. Despite multi-modal aggressive treatment including surgical resection, chemotherapy, and radiation, five-year overall survival remains poor at 35%. Due to its
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service