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F0502

D-Fructose 1,6-bisphosphate dicalcium salt

Name: <SC>D</SC>-Fructose 1,6-bisphosphate dicalcium salt
Brand: SIGMA

practical grade, ~70%

Synonym(s):

D(+)Fructofuranose 1,6-diphosphate, Harden-Young ester, Hexose diphosphate

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₀Ca₂O₁₂P₂

CAS Number:

6055-82-9

Molecular Weight:

416.24

EC Number:

227-979-9

MDL number:

MFCD00135875

UNSPSC Code:

12352201

PubChem Substance ID:

24894723

grade

practical grade

Assay

~70%

form

solid

SMILES string

[Ca].OC(COP(O)(O)=O)C(O)C(O)C(=O)COP(O)(O)=O

InChI

1S/C6H14O12P2.Ca.2H/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16;;;/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16);;;

InChI key

KJZXQSWXBTUHIN-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The effects of fructose-1,6-diphosphate on haemodynamic parameters and survival in a rodent model of propranolol and verapamil poisoning.

Yasmean Kalam et al.

Clinical toxicology (Philadelphia, Pa.), 50(7), 546-554 (2012-08-09)

Fructose-1,6-diphosphate (FDP) is a metabolite in the glycolytic pathway created from glucose. Exogenously administered FDP increases the yield of ATP from anaerobic glycolysis. FDP reduces ischaemic tissue area in experimentally-induced cerebral and myocardial infarction and improves haemodynamics post-cardiac bypass. We

Comparison of sildenafil with strontium fructose diphosphate in improving erectile dysfunction against upregulated cavernosal NADPH oxidase, protein kinase Cε, and endothelin system in diabetic rats.

Ming Xu et al.

The Journal of pharmacy and pharmacology, 64(2), 244-251 (2012-01-10)

Phosphodiesterase type 5 inhibitors are potent in relieving erectile dysfunction (ED), however, they are less satisfactory in diabetic patients, probably due to the pro-inflammatory biomarkers caused by diabetes. Therefore, it was interesting to compare the effects of sildenafil with strontium

Further unraveling the regulatory twist by elucidating metabolic coinducer-mediated CbbR-cbbI promoter interactions in Rhodopseudomonas palustris CGA010.

Gauri S Joshi et al.

Journal of bacteriology, 194(6), 1350-1360 (2012-01-17)

The cbb(I) region of Rhodopseudomonas palustris (Rp. palustris) contains the cbbLS genes encoding form I ribulose-1,5-bisphosphate (RuBP) carboxylase oxygenase (RubisCO) along with a divergently transcribed regulator gene, cbbR. Juxtaposed between cbbR and cbbLS are the cbbRRS genes, encoding an unusual

Fructose-1,6-bisphosphate and N-acetylcysteine attenuate the formation of advanced oxidation protein products, a new class of inflammatory mediators, in vitro.

Guilherme Vargas Bochi et al.

Inflammation, 35(6), 1786-1792 (2012-07-11)

The accumulation of advanced oxidation protein products (AOPP) has been linked to several pathological conditions. Previous studies have identified AOPP as a novel biomarker of oxidative damage to proteins and a novel class of mediator of inflammation. The aim of

Fructose-1,6-bisphosphate protects against Zymosan-induced acute lung injury in mice.

Roberto Christ Vianna Santos et al.

Inflammation, 35(3), 1198-1203 (2012-02-14)

It has been previously showed that fructose-1,6-bisphosphate (FBP) has anti-inflammatory and immunomodulatory effects on several experimental inflammation models. However, the effects and mechanism of FBP on Zymosan-induced acute lung injury (ALI) in mice had not been tested. In this study

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