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EMU086551

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Slc2a4

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGCATGGGTTTCCAGTATGTTGCGGATCGTATGGGTCCTTACGTCTTCCTTCTATTTGCCGTCCTCCTGCTTGGCTTCTTCATCTTCACCTTCCTAAAAGTGCCTGAAACCAGAGGCCGGACGTTTGACCAGATCTCAGCTGCCTTCCGACGGACACCTTCCCTTTTAGAGCAGGAGGTGAAACCCAGTACAGAACTTGAATACTTAGGGCCAGATGAGAATGACTGAGGGGCAAAACAGGGTGGGAGAGCCACCTCTCCACCCAGACTCCCTCCTTTCCTCTACAGCACTTTAGCCCTCTCTTCCCTGTTACCTCCAGGTTGAAGGAACAGCAGCCTGGGGAACTGGGAAGCTGAAGGGAGGGGTGGTCCATGTACCCCTCATTCCCCCTGTGTGATTCTTTTGGATTATTTATGTGTGTGGCTAGGCTGTGGCCACCTAGATGGGCTTTCTCCGTCCTGCCTTCCTCCTGCCCCTACCCAGACTCAGCTCTAGACTACTTTCCTCCCCTTTCGAGA

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Jessy Anthony et al.
PloS one, 8(10), e77946-e77946 (2013-11-07)
Insulin resistance is a characteristic feature of Type 2 diabetes. Insulin resistance has also been implicated in the pathogenesis of cardiovascular disease. Currently used thiazolidinedione (TZD) insulin sensitizers although effective, have adverse side effects of weight gain, fluid retention and
Ann Hammarstedt et al.
Scientific reports, 8(1), 15757-15757 (2018-10-27)
Adipose tissue dysfunction is considered an important contributor to systemic insulin resistance and Type 2 diabetes (T2D). Recently, a novel family of endogenous lipids, palmitic acid hydroxy stearic acids (PAHSAs), was discovered. These have anti-diabetic and anti-inflammatory effects in mice

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