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B6768

Sigma-Aldrich

Boric acid

BioReagent, for molecular biology, suitable for cell culture, suitable for plant cell culture, ≥99.5%

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About This Item

Linear Formula:
H3BO3
CAS Number:
10043-35-3
Molecular Weight:
61.83
EC Number:
233-139-2
MDL number:
MFCD00011337
UNSPSC Code:
12161700
eCl@ss:
38120104
PubChem Substance ID:
24891821
NACRES:
NA.25
grade:
for molecular biology
pH:
5.1 (25 °C, 1.8 g/L)
Pricing and availability is not currently available.

grade

for molecular biology

Quality Level

200

vapor pressure

2.6 mmHg ( 20 °C)

product line

BioReagent

Assay

≥99.5%

form

powder

technique(s)

cell culture | mammalian: suitable
cell culture | plant: suitable

pH

5.1 (25 °C, 1.8 g/L)

mp

160 °C (dec.) (lit.)

solubility

water: 40 mg/mL, clear, colorless

density

1.49 g/cm3 at 23 °C

cation traces

Fe: ≤5 ppm
Mg: ≤5 ppm
heavy metals (as Pb): ≤10 ppm

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

foreign activity

DNase, RNase, and protease, none detected

storage temp.

room temp

SMILES string

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

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General description

Boric acid is a weak monobasic Lewis acid (electron pair acceptor), which reacts reversibly with alcohols. It is used in dermal and women′s hygiene products due to its mild antibacterial and antifungal effects. Boric acid is used as a buffer in ophthalmic products. It acts as an effective solid lubrication agent because of its molecular structure. Boric acid finds its applications in glass making, fire retardant. Boric acid is used in biochemistry in buffer solutions. It also forms complex equilibria in solution, with the tetraborate ion (B4O7 2- ) being the predominant species. Borate buffers are involved in discontinuous electrophoresis and capillary electrophoresis systems for the separation of proteins and nucleic acids.

Application

Boric acid has been used:
  • to prepare boric buffer for the quantification of primary amine groups at the surface of nanocapsules
  • to study its effects on epigenetic change
  • for the estimation of protein in wheatgrass using Kjeldahl method

Used to promote amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents.
Intensified Azeotropic Distillation: A Strategy for Optimizing Direct Amidation

Features and Benefits

  • Environment-friendly
  • Non-toxic 

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360FD

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM5037
BCCL9192
BCCL9191
BCCL4743
BCCL4742

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Calvin S Carter et al.
Cell metabolism, 32(4), 561-574 (2020-10-08)
Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained approach would enable the long-term control of redox signaling for
Joy E Kirkpatrick et al.
Epigenetics, 13(5), 557-572 (2018-06-22)
Periodontal disease (PD) afflicts 46% of Americans with no effective adjunctive therapies available. While most pharmacotherapy for PD targets bacteria, the host immune response is responsible for driving tissue damage and bone loss in severe disease. Herein, we establish that
C A Yoder et al.
Poultry science, 85(7), 1285-1293 (2006-07-13)
Nicarbazin (NCZ) is an anticoccidial drug routinely used in the poultry industry that can negatively affect reproduction by reducing egg production, egg weight, and egg hatchability. The molecular mechanisms by which NCZ affects reproduction are unknown. Lipoprotein lipase, vitellogenin, transglutaminase
Lisa M Røst et al.
Metabolites, 10(2) (2020-02-26)
Absolute quantification of intracellular metabolite pools is a prerequisite for modeling and in-depth biological interpretation of metabolomics data. It is the final step of an elaborate metabolomics workflow, with challenges associated with all steps-from sampling to quantifying the physicochemically diverse
Akie Shimotohno et al.
Plant & cell physiology, 56(4), 620-630 (2015-02-12)
Boron, an essential micronutrient, is transported in roots of Arabidopsis thaliana mainly by two different types of transporters, BORs and NIPs (nodulin26-like intrinsic proteins). Both are plasma membrane localized, but have distinct transport properties and patterns of cell type-specific accumulation
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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How can I find out the expiration date? Lot No : BCCH1940

    1 answer

    1. Expiration information will be on the certificate of analysis. The certificate of analysis can be accessed by clicking on the "COO/COA" tab under the product photo the product detail page or the scrolling down to the documentation section. Here is a copy of lot BCCH1940 COA: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/B6768-BULKBCCH1940.pdf.

      This product does not contain an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services

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