95209

L-Ascorbic acid

BioUltra, ≥99.5% (RT)

• Synonym(s): L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
• Empirical Formula (Hill Notation): C₆H₈O₆
• CAS Number: 50-81-7
• Molecular Weight: 176.12
• Beilstein: 84272
• EC Number: 200-066-2
• MDL number: MFCD00064328
• UNSPSC Code: 12352205
• PubChem Substance ID: 57653659
• NACRES: NA.79

Properties

• biological source: synthetic
• Quality Level: 200
• product line: BioUltra
• Assay: ≥99.5% (RT)
• form: powder or crystals
• impurities: insoluble matter, passes filter test
• ign. residue: ≤0.05% (as SO₄)
• loss: ≤0.05% loss on drying, 20 °C (HV)
• color: white to off-white
• pH: 1.0-2.5 (25 °C, 1 M in H₂O)
• mp: 190-194 °C (dec.)
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤20 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤25 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: cut-off at 306 nm in H₂O at 1 M
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• InChI key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
• Gene Information: human ... SLC23A2(9962)

Description

General description

L-Ascorbic acid, also known as vitamin C, is a water-soluble vitamin.[1] It is naturally present in a variety of foods such as citrus fruits and vegetables. It is present only in minimal amount in milk.[2]

Application

L-Ascorbic acid has been used as an antioxidant supplement in incubation solution for dissected and sliced brain sections.[3][4] It has also been used as a supplement in phosphate-buffered saline (PBS) wash buffer during oxidative GFP chromophore formation.[5]

Biochem/physiol Actions

L-Ascorbic acid (Vitamin C) acts as a potential anti-oxidant[6] and reducing agent.[7] It prevents bacterial mutagenesis induced by N-nitroso compounds.[8] In plants, vitamin C elicits several cellular processes such as growth, apoptosis, pathogen responses, hormone responses, flowering and senescence, and protection against environmental stresses. [7] Vitamin C deficiency is associated with the development of scurvy, prominent - gingivitis, perifollicular hemorrhages, poor wound healing, petechiae and ecchymosis.[2]

Other Notes

Denaturation of proteins[9]; Dimeric association of E. coli RNA polymerase α subunits, studied by cleavage of single cysteine α subunits conjugated to Fe-BABE[10].

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves