All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C21H25ClN2O3 · 2HCl
CAS Number:
Molecular Weight:
461.81
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.25
Pricing and availability is not currently available.
Recommended Products
Quality Level
Assay
≥98.0% (HPLC)
form
powder
SMILES string
Cl[H].Cl[H].OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI
1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
InChI key
PGLIUCLTXOYQMV-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
Application
Cetirizin (CTZ) may be used in studies on the treatment of cutaneous mastocytosis (urticaria pigmentosa). Cetirizin, an antihistamine, may be useD in allergy research as an antagonist of the histamine 1 receptor (H1R).
Signal Word
Warning
Hazard Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
M Gschwandtner et al.
Allergy, 68(1), 37-47 (2012-11-20)
Defects in keratinocyte differentiation and skin barrier are important features of inflammatory skin diseases like atopic dermatitis. Mast cells and their main mediator histamine are abundant in inflamed skin and thus may contribute to disease pathogenesis. Human primary keratinocytes were
K Rossbach et al.
Neuroscience, 190, 89-102 (2011-06-22)
Histamine has long been recognised as a classical inducer of pruritus. However, the specific mechanism of histamine-induced itch has still not been fully understood. The H1 and H4 receptor appear to be key components in the induction of itch. The
Ko-Haung Lue et al.
International journal of pediatric otorhinolaryngology, 76(7), 994-1001 (2012-04-20)
Supplementary consumption of probiotics may temporarily alter the intestinal microflora of infants and children, thereby preventing and treating allergic disorders. To compare the clinical efficacy of levocetirizine with that of levocetirizine plus Lactobacillus johnsonii EM1 (Lj EM1) for treating perennial
Susan D Mathias et al.
Allergy and asthma proceedings, 33(2), 186-190 (2012-04-25)
The Urticaria Patient Daily Diary, including the Urticaria Activity Score, has recently been validated in adults with chronic idiopathic urticaria (CIU), but its validity in adolescents is unknown. This study was designed to (1) assess the content validity of the
Céline Caillet et al.
British journal of clinical pharmacology, 74(5), 886-889 (2012-03-13)
The physicochemical properties of racemates and stereoisomers of medicines can differ significantly, and this may affect the side-effect profile in addition to the pharmacokinetics and intended pharmacology. This is a study to investigate the profile of adverse drug reactions of
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
