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S5631

Sigma-Aldrich

Silicon dioxide

~99%, 0.5-10 μm (approx. 80% between 1-5 μm)

Synonym(s):

Sand, white quartz, Quartz, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
14808-60-7
Molecular Weight:
60.08
EC Number:
238-878-4
MDL number:
MFCD00011232
UNSPSC Code:
12352300
PubChem Substance ID:
329824458
NACRES:
SB.52

Assay

~99%

form

powder

particle size

0.5-10 μm (approx. 80% between 1-5 μm)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Linkage

Historically called amorphous.

Preparation Note

A naturally occurring microcrystalline silica which has been finely ground.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alida Kent et al.
Journal of tropical medicine, 2013, 324140-324140 (2013-11-07)
Cutaneous leishmaniasis (CL) is an emerging disease in Suriname, with at least 200 cases per year. Little is known about the biology of CL in the country. The most important parasite species is Leishmania Viannia guyanensis, but possible vectors and
Yan Liu et al.
Respiratory research, 18(1), 38-38 (2017-02-23)
Myofibroblasts play a major role in the synthesis of extracellular matrix (ECM) and the stimulation of these cells is thought to play an important role in the development of silicosis. The present study was undertaken to investigate the anti-fibrotic effects
Jian-Feng Li et al.
Plant methods, 6(1), 1-1 (2010-02-26)
Research in plant molecular biology involves DNA purification on a daily basis. Although different commercial kits enable convenient extraction of high-quality DNA from E. coli cells, PCR and agarose gel samples as well as plant tissues, each kit is designed
Haijun Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 310(2), L121-L132 (2015-11-27)
Silicosis is a systemic disease caused by inhaling silicon dioxide (SiO2). Phagocytosis of SiO2 in the lungs initiates an inflammatory cascade that results in fibroblast proliferation and migration followed by fibrosis. According to previous data from our laboratory, monocyte chemotactic
Haijun Liu et al.
Particle and fibre toxicology, 13(1), 55-55 (2016-10-27)
Silicosis is characterized by accumulation of fibroblasts and excessive deposition of extracellular matrix. Monocyte chemotactic protein-1-induced protein 1 (MCPIP1) plays a critical role in fibrosis induced by SiO2. However, the details of the downstream events of MCPIP1 activity in pulmonary
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