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Y0000481

Dibrompropamidine for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dibrompropamidine diisetionate

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About This Item

Empirical Formula (Hill Notation):
C21H30Br2N4O10S2
CAS Number:
614-87-9
Molecular Weight:
722.42
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

dibrompropamidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(O)CCO.Brc1c(ccc(c1)\C(=N\[H])\N)OCCCOc2c(cc(cc2)\C(=N\[H])\N)Br

InChI

1S/C17H18Br2N4O2.C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);3H,1-2H2,(H,4,5,6)

InChI key

BZACJASHKPPTKX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dibrompropamidine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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D Boillot et al.
Diabetologia, 28(6), 359-364 (1985-06-01)
The antiprotozoal drug pentamidine can be toxic to islet cells in vivo and in vitro. Rat islets were exposed to pentamidine (mesylate and isethionate salts) and six other structurally related diamidines. The beta-cell response to arginine + theophylline was suppressed
[When the treatment is the problem].
Dag Sollesnes Holsen
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 129(4), 307-307 (2009-02-24)
M T Suller et al.
The Journal of hospital infection, 43(4), 281-291 (2000-02-05)
Concern has been growing regarding the potential of antibiotic and disinfectant co-resistance in clinically important bacteria. In this study, the susceptibilities of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) to chlorhexidine (CHX), the quaternary ammonium compounds cetylpyridinium chloride
S S Asghar et al.
Biochimica et biophysica acta, 317(2), 539-548 (1973-08-30)
A series of amidino compounds has been investigated for their inhibitory effects on C1s, C1r, and generation of C1s. Diamidines consisting of two amidinophenyl residues linked in para position by a molecular bridge proved to be the strongest competitive inhibitors
Allergic contact dermatitis from dibrompropamidine cream.
C Lützow-Holm
Contact dermatitis, 20(2), 160-160 (1989-02-01)
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