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SMB01373

Sigma-Aldrich

2-Hydroxyesterone

≥95% (HPLC)

Synonym(s):

2-Hydroxyesterone, 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one, 2-Hydroxy estrone, 2-OH-E1, 2-OHE2, 2OHE1, Catecholestrone

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About This Item

Empirical Formula (Hill Notation):
C18H22O3
CAS Number:
362-06-1
Molecular Weight:
286.37
MDL number:
MFCD32173801
UNSPSC Code:
51351610
NACRES:
NA.21

biological source

synthetic

Quality Level

200

Assay

≥95% (HPLC)

form

solid

storage temp.

2-8°C

InChI

1S/C18H22O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,19-20H,2-7H2,1H3/t11-,12+,14-,18-/m0/s1

InChI key

SWINWPBPEKHUOD-JPVZDGGYSA-N

Application

2-Hydroxyestrone (2OHE1) is a metabolite of the endogenous estrogen estrone. 2OHE1 is formed predominantly by the action of cytochrome P450 (CYP) enzymes CYP1A1, CYP1A2, and CYP1B1. 2OHE1 and 16OHE1 are reported to be associated with breast carcinogenesis.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000271609
0000195312
0000204126
0000204125

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