Skip to Content
Merck
All Photos(1)

Documents

B5899

Supelco

Buflomedil hydrochloride

analytical standard

Synonym(s):

4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H25NO4 · HCl
CAS Number:
35543-24-9
Molecular Weight:
343.85
EC Number:
252-611-9
MDL number:
MFCD00078965
UNSPSC Code:
41116107
PubChem Substance ID:
329773268
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H

InChI key

ZDPACSAHMZADFZ-UHFFFAOYSA-N

Gene Information

human ... EBP(10682)

Looking for similar products? Visit Product Comparison Guide

General description

Buflomedil hydrochloride is a vasoactive agent. Its mode of action involves increasing the peripheral and cerebral blood flow in ischaemic tissues of patients, who are mostly affected with vascular diseases.

Application

Buflomedil hydrochloride may be used as an analytical standard for the determination of buflomedil in biological matrices using high-performance liquid chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations and serum samples using electroanalytical and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
038F09711
038F0971

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Paul P Dobesh et al.
Pharmacotherapy, 29(5), 526-553 (2009-04-29)
Peripheral artery disease, defined as atherosclerosis in the lower extremities, affects nearly 8.5 million people in the United States. Due to the frequent asymptomatic manifestation of peripheral artery disease, diagnosis may be delayed and its true incidence underestimated. However, some
Danik Arana Navarte et al.
Medical problems of performing artists, 26(2), 79-83 (2011-06-23)
Determine the safety and tolerance of mesotherapy as a technique for the treatment of musculoskeletal complaints in musicians. 67 patients (55.2% women) were subjected to a total of 267 mesotherapy sessions. A mesotherapy needle or normal needle was used randomly.
Buflomedil: still too many fatal cardiac and neurological events.
Prescrire international, 20(115), 99-99 (2011-06-09)
Claudio Bucolo et al.
Pharmacoepidemiology and drug safety, 21(11), 1190-1196 (2012-08-03)
Review all the individualized cases of adverse drug reaction (ADR) potentially related to buflomedil, a vasodilator with the indication for peripheral arterial disease (PAD), marketed in Europe since the 1970s but recently suspended by the European Medicines Agency. A review
Quantification of the Vasoactive Agent Buflomedil HCl in Pharmaceutical Formulation and Human Serum by Stripping Voltammetry and Liquid Chromatography
El-Desoky.SH, et al.
Acta Chimica Slovenica, 57(2), 18-21 (2010)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service