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Key Documents

24-1440

Sigma-Aldrich

Phenolphthalein

JIS special grade, ≥98.0%

Synonym(s):

3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone

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About This Item

Empirical Formula (Hill Notation):
C20H14O4
CAS Number:
Molecular Weight:
318.32
Colour Index Number:
764
Beilstein:
284423
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
Pricing and availability is not currently available.

grade

JIS special grade

Assay

≥98.0%

form

solid

availability

available only in Japan

mp

261-263 °C (lit.)

solubility

acetone: soluble

SMILES string

Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4

InChI

1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

InChI key

KJFMBFZCATUALV-UHFFFAOYSA-N

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Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 1B - Muta. 2 - Repr. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Edward Bormashenko et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 10(4), 654-656 (2009-01-30)
The mechanisms of floating and sliding of liquid marbles are studied. Liquid marbles containing CaCl(2) and marbles containing NaOH water solutions float on water containing Na(2)CO(3) and an alcoholic solution of phenolphthalein with no chemical reaction. Sliding of liquid marbles
Stefano Mangani et al.
Journal of medicinal chemistry, 54(15), 5454-5467 (2011-06-24)
To identify specific bacterial thymidylate synthase (TS) inhibitors, we exploited phenolphthalein (PTH), which inhibits both bacterial and human enzymes. The X-ray crystal structure of Lactobacillus casei TS (LcTS) that binds PTH showed multiple binding modes of the inhibitor, which prevented
H Wang et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(8), 1194-1201 (2012-07-13)
Desorption corona beam ionisation (DCBI), the relatively novel ambient mass spectrometry (MS) technique, was utilised to screen for illicit additives in weight-loss food. The five usually abused chemicals - fenfluramine, N-di-desmethyl sibutramine, N-mono-desmethyl sibutramine, sibutramine and phenolphthalein - were detected
Pieter A Cohen et al.
Journal of general internal medicine, 27(1), 51-56 (2011-08-17)
Pai You Guo is a weight loss supplement manufactured in China and adulterated with the banned pharmaceutical products sibutramine and phenolphthalein. The US Food and Drug Administration (FDA) announced a voluntary recall of Pai You Guo in 2009, yet clinicians
Ann M Dring et al.
Chemico-biological interactions, 188(3), 512-525 (2010-09-28)
Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are closely related orphan nuclear receptor proteins that share several ligands and target overlapping sets of genes involved in homeostasis and all phases of drug metabolism. CAR and PXR are involved

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