Chemical communications (Cambridge, England), 47(44), 12158-12160 (2011-10-12)
A novel fluorescent sensor for the detection of Hg(2+) in aqueous media was developed. The method takes advantages of the highly selective thymine-Hg(2+)-thymine coordination and the sensitive "signal-on" structure-switching molecular beacon.
European journal of cancer (Oxford, England : 1990), 48(13), 2075-2085 (2011-11-11)
Carcinogenic potential of argemone oil (AO) and butter yellow (BY), the adulterants encountered in edible oil, in gall bladder of Swiss albino mice was undertaken to investigate the potential aetiological factors of gall bladder carcinoma (GBC) in the Indo-Gangetic basin.
N-6 methylation of adenine destabilises duplex DNA and this can increase the proportion of DNA that dissociates into single strands. We have investigated utilising this property to measure the DNA adenine methyltransferase-catalyzed conversion of hemimethylated to fully methylated DNA through
Journal of biomolecular structure & dynamics, 29(1), 27-50 (2011-06-24)
Oligonucleotides find several numbers of applications: as diagnostic probes, RT and PCR primers and antisense agents due to their ability of forming specific interactions with complementary nucleotide sequences within nucleic acids. These interactions are strongly affected by accessibility of the
In this paper, we constructed a new electrochemical biosensor for DNA detection based on a molecule recognition technique. In this sensing protocol, a novel dual-labeled DNA probe (DLP) in a stem-loop structure was employed, which was designed with dabcyl labeled
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