T-085

Tizanidine hydrochloride

500 μg/mL in methanol, certified reference material, Cerilliant^®

• Synonym(s): 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride
• Empirical Formula (Hill Notation): C₉H₉Cl₂N₅S
• CAS Number: 64461-82-1
• Molecular Weight: 290.17
• MDL number: MFCD00798231
• UNSPSC Code: 41116107
• PubChem Substance ID: 329826628
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 500 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: Cl[H].Clc1ccc2nsnc2c1NC3=NCCN3
• InChI: 1S/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
• InChI key: ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
• Gene Information: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Description

General description

Tizanidine, sold under the tradename Zanaflex, is a skeletal muscle relaxant used for treatment of spasticity associated with multiple sclerosis, and for painful muscle spasms. This certified solution standard is suitable for numerous GC/MS and LC-MS/MS tizanidine testing applications in clinical toxicology, urine drug testing, pain prescription monitoring or forensic analysis.

Biochem/physiol Actions

α₂-adrenoceptor agonist.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup