D-041

Dextrorphan-d₃

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₇H₂₀D₃NO
• CAS Number: 524713-57-3
• Molecular Weight: 260.39
• EC Number: 200-659-6
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H]C([2H])([2H])N1CC[C@@]23CCCCC2[C@@H]1Cc4ccc(O)cc34
• InChI: 1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14?,16-,17-/m0/s1/i1D3
• InChI key: JAQUASYNZVUNQP-XZSBYTENSA-N

Description

General description

An internal standard for dextromethorphan or dextrorphan testing by GC/MS or LC/MS for clinical toxicology, forensic testing, P450 trials, or pharmaceutical research. Dextrorphan is a primary metabolite of dextromethorphan in blood. Dextromethorphan, an active ingredient in many over-the-counter cold and cough medicines, is used recreationally as a hallucinogen with effects similar to ketamine and phencyclidine (PCP).

Application

• Cannabinoid Receptor Binding Studies: Research exploring the interaction of (-)-trans- Δ⁹-THC with cannabinoid receptors underlines the utility of pharmaceutical grade (-)-trans- Δ⁹-THC for receptor binding studies, offering a deeper understanding of cannabinoid receptor dynamics (Frantzeskaki et al., 2024).


• Development of Biochemical Assays: The development of biochemical assays for cannabinoids utilizes synthetic (-)-trans- Δ⁹-THC, demonstrating its role in high-throughput screening for cannabinoid activity, which is crucial for advancing cannabinoid research (Ferreira et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup