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Sigma-Aldrich

L-Lysine-4,4,5,5-d4 hydrochloride

98 atom % D, 98% (CP)

Synonym(s):

SILAC Amino Acid, (S)-2,6-Diaminocaproic acid-4,4,5,5-d4 hydrochloride, Deuterated Lys, Deuterated lysine

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About This Item

Linear Formula:
H2NCH2(CD2)2CH2CH(NH2)CO2H · HCl
CAS Number:
Molecular Weight:
186.67
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.12

isotopic purity

98 atom % D

Assay

98% (CP)

form

solid

optical activity

[α]25/D +20.7°, c = 2 in 5 M HCl

technique(s)

protein expression: suitable

mp

263-264 °C (dec.) (lit.)

mass shift

M+4

SMILES string

Cl.[2H]C([2H])(CN)C([2H])([2H])C[C@H](N)C(O)=O

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1/i1D2,2D2;

InChI key

BVHLGVCQOALMSV-UGJIAQRQSA-N

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Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zhifei Chen et al.
Journal of agricultural and food chemistry, 67(19), 5634-5646 (2019-04-25)
Proteins present in infant formulas are modified by oxidation and glycation during processing. Modified amino acid residues released from proteins may be absorbed in the gastrointestinal tract, and pose a health risk to infants. In this study, the markers of
Mohammad Sedigh Jasour et al.
Journal of agricultural and food chemistry, 65(48), 10673-10684 (2017-11-10)
The effect of partially replacing fishmeal in aquafeed with feathermeal (FTH) at three levels (0%: FTH0, 8%: FTH8, 24%: FTH24) and two extrusion temperatures (100 and 130 °C) was evaluated in rainbow trout (Oncorhynchus mykiss) with respect to growth performance
Zhifei Chen et al.
Free radical research, 53(1), 68-81 (2019-01-17)
Modification of proteins in infant milk formula (IF) is of major concern to the dairy industry and consumers. Thermal treatment is required for microbiological safety, but heat, light, metal-ions and other factors may induce oxidative damage, and be a health
Flavia Bianchi et al.
Insects, 11(11) (2020-11-22)
The production of phagostimulant and attractive volatile organic compounds (VOCs) by yeasts can be exploited to improve the efficacy of attract-and-kill formulations against the spotted wing drosophila (SWD). This study evaluated the persistence over one week of a yeast-based formulation
Ville Paakinaho et al.
Nucleic acids research, 49(4), 1951-1971 (2021-02-02)
Glucocorticoid receptor (GR) is an essential transcription factor (TF), controlling metabolism, development and immune responses. SUMOylation regulates chromatin occupancy and target gene expression of GR in a locus-selective manner, but the mechanism of regulation has remained elusive. Here, we identify

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