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Sigma-Aldrich

Poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol)

average Mn ~3,300

Synonym(s):

Pluronic® 31R1, PPG-PEG-PPG

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About This Item

CAS Number:
691397-13-4
MDL number:
MFCD00082049
UNSPSC Code:
12352112
PubChem Substance ID:
24867240
NACRES:
NA.23

form

viscous liquid

mol wt

average Mn ~3,300

composition

PEG, 10 wt. %

refractive index

n20/D 1.454

surface tension

34 dyn/cm, 25 °C, 0.1 wt. % in H2O

viscosity

660 cP(25 °C, Brookfield)(lit.)

transition temp

softening point −25 °C
cloud point 25 °C (1 wt. % aqueous solution)

density

1.018 g/mL at 25 °C

HLB

2.0 - 7.0

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

General description

Surface activity of the polymer is dependent on the EO/PO ratio. PPG-PEG-PPG exhibits lower foaming, greater defoaming and reduced gelling tendencies relative to Pluronic® surfactants. Terminal secondary hydroxyl groups of PPG-PEG-PPG have lower reactivity and acidity than the primary hydroxyl groups in Pluronic surfactants.

Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.
PPG-PEG-PPG Pluronic® 31R1 can be used as surface cleaners (soft and hard), defoamers in coatings, in water treatment, lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.

Features and Benefits

Surface activity is dependent on the EO/PO ratio. Lower foaming, greater defoaming and reduced gelling tendencies relative to Pluronic® surfactants. Terminal secondary hydroxyl groups have lower reactivity and acidity than the primary hydroxyl groups in Pluronic® surfactants.

Legal Information

Pluronic is a registered trademark of BASF

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
D J Bartley et al.
Veterinary parasitology, 187(3-4), 464-472 (2012-03-21)
Non-specific mechanisms involving ATP-binding cassette drug efflux transporters may play an important role in xenobiotic clearance in ovine gastro-intestinal nematodes. By using transporter inhibitors, the aim of this trial was to assess the possibility of increasing drug bioavailability in the
Neeta Jain-Gupta et al.
FEMS immunology and medical microbiology, 66(3), 436-444 (2012-11-21)
Brucellosis is the most common zoonotic disease worldwide, and there is no vaccine for human use. Brucella melitensis Rev1, a live attenuated strain, is the commercial vaccine for small ruminants to prevent B. melitensis infections but has been associated with abortions
Wanhua Feng et al.
Colloids and surfaces. B, Biointerfaces, 105, 43-50 (2013-01-29)
The interaction between bacteria and surfaces is central to many environmental, industrial and medical applications. Surfactants are commonly used in these applications and can potentially influence the bacterium/surface interaction. The effect of surfactants upon bacterial cell surface thermodynamic properties was
Jianan Shen et al.
Biomaterials, 33(33), 8613-8624 (2012-08-23)
Drug resistance is a main obstacle for the successful chemotherapy of lung cancer. In this work, a new co-delivery system, P85-PEI/TPGS/PTX/shSur complex nanoparticles (PTPNs), to overcome paclitaxel (PTX) resistance in A549 human lung cancer was designed and developed. The experimental
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