417122

N,N-Diethylnipecotamide

98%

• Synonym(s): N,N-Diethyl-3-piperidinecarboxamide, Piperidine-3-carboxylic acid diethylamide
• Empirical Formula (Hill Notation): C₁₀H₂₀N₂O
• CAS Number: 3367-95-1
• Molecular Weight: 184.28
• EC Number: 222-136-1
• MDL number: MFCD00005990
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866122

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.489 (lit.)
• bp: 111 °C/6.1 mmHg (lit.)
• density: 0.989 g/mL at 25 °C (lit.)
• SMILES string: CCN(CC)C(=O)C1CCCNC1
• InChI: 1S/C10H20N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h9,11H,3-8H2,1-2H3
• InChI key: ZXQKYQVJDRTTLZ-UHFFFAOYSA-N

Description

General description

N,N-Diethylnipecotamide is a six-membered bidentate chelating ligand. It participates as ligand in the synthesis of dimeric halocopper(I) complexes.

Application

N,N-Diethylnipecotamide may be used for the preparation of 1-substituted N,N-diethylnipecotamides.

Reactant for synthesis of:
Antituberculosis drugs
Spiroimidazolidinone NPC1L1 inhibitors
Acyl-CoA:cholesterol acyltransferase inhibitors
Alpha 7 nicotinic acetylcholine receptor agonist
Antimycobacterials
Isocyanoamides useful as starting materials in IMCR

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves