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243868

Sigma-Aldrich

2-Octynoic acid

98%

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About This Item

Linear Formula:
CH3(CH2)4C≡CCO2H
CAS Number:
Molecular Weight:
140.18
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

98%

refractive index

n20/D 1.46 (lit.)

bp

148-149 °C/19 mmHg (lit.)

mp

2-5 °C (lit.)

density

0.961 g/mL at 25 °C (lit.)

SMILES string

CCCCCC#CC(O)=O

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

213.8 °F - closed cup

Flash Point(C)

101 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Lana S Barkawi et al.
Insect biochemistry and molecular biology, 33(8), 773-788 (2003-07-25)
The pheromone component, frontalin (1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane) is thought to be formed in Dendroctonus spp. bark beetles through the cyclization of oxygenated 6-methyl-6-hepten-2-one (6-MHO). Unlike many of the isoprenoid pheromone components of bark beetles, there is no obvious immediate host conifer precursor
Maria Vølund Heisterberg et al.
Contact dermatitis, 62(2), 97-101 (2010-02-09)
Methyl 2-octynoate is a synthetic fragrance which was first described to have sensitizing properties in 1935. It is one of the 26 fragrances to be labelled on the ingredient list according to current European cosmetics regulation. To report the experience
Amy Dhirapong et al.
Hepatology (Baltimore, Md.), 57(2), 708-715 (2012-09-22)
Collectively, the data in both humans and murine models of human primary biliary cirrhosis (PBC) suggest that activated T cells, particularly CD8 T cells, play a critical role in biliary cell destruction. Under physiological conditions, T-cell activation involves two critical
J A Montgomery et al.
Biomedical & environmental mass spectrometry, 18(6), 416-423 (1989-06-01)
Rats given 2-octynoic acid by intraperitoneal injection excrete elevated amounts of medium-chain dicarboxylic acids and other acidic metabolites usually associated with human medium-chain acyl-CoA dehydrogenase deficiency. Onset of this organic acid profile is immediate and lasts for approximately 24 h.
Phornnop Naiyanetr et al.
Journal of autoimmunity, 37(3), 209-216 (2011-07-19)
Our laboratory has hypothesized that xenobiotic modification of the native lipoyl moiety of the major mitochondrial autoantigen, the E2 subunit of the pyruvate dehydrogenase complex (PDC-E2), may lead to loss of self-tolerance in primary biliary cirrhosis (PBC). This thesis is

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