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202789

Sigma-Aldrich

Beryllium sulfate tetrahydrate

99.99% trace metals basis

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About This Item

Linear Formula:
BeSO4 · 4H2O
CAS Number:
7787-56-6
Molecular Weight:
177.14
EC Number:
236-842-2
MDL number:
MFCD00149156
UNSPSC Code:
12352302
PubChem Substance ID:
24852118
NACRES:
NA.22

Assay

99.99% trace metals basis

density

1.713 g/mL at 25 °C (lit.)

SMILES string

[Be++].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[O-]S([O-])(=O)=O

InChI

1S/Be.H2O4S.4H2O/c;1-5(2,3)4;;;;/h;(H2,1,2,3,4);4*1H2/q+2;;;;;/p-2

InChI key

DIMYTQPLZWDZFE-UHFFFAOYSA-L

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Application

Used in study of the dicarboxylate chelation of beryllium in an attempt to understand its physiological chemistry.

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

Target Organs

Respiratory system, Skin,Respiratory Tract

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCH6025
MKCG4241
MKCC1678
MKBP5108V
MKAA3609

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Michael Schmidt et al.
Inorganic chemistry, 36(10), 2040-2043 (1997-05-07)
Maleic and phthalic acids are found to react with Be(OH)(2), generated in situ from BeSO(4)(aq) and Ba(OH)(2)(aq), in aqueous solution at pH 3.0 or 4.4, respectively (25 degrees C), to give solutions containing the complexes (H(2)O)(2)Be[(OOCCH)(2)] (1) and (H(2)O)(2)Be[(OOC)(2)C(6)H(4)] (3).
Chadi H Stephan et al.
Journal of applied toxicology : JAT, 29(1), 27-35 (2008-09-13)
Occupational exposure to beryllium may cause chronic beryllium disease (CBD), a granulomatous interstitial pneumonitis caused by a cell-mediated immune response with delayed hypersensitivity initiated by an electrostatic interaction with the MHC class II human leukocyte antigen (HLA). Increased research efforts
S S Tinkle et al.
Journal of immunology (Baltimore, Md. : 1950), 163(5), 2747-2753 (1999-08-24)
Chronic beryllium disease (CBD) provides a human disorder in which to study the delayed type IV hypersensitivity response to persistent Ag that leads to noncaseating pulmonary granuloma formation. We hypothesized that, in CBD, failure of IL-10 to modulate the beryllium-specific
D Zissu et al.
Contact dermatitis, 34(3), 196-200 (1996-03-01)
An experimental study was conducted in guinea pigs for the predictive assessment of the beryllium alloy hazard in occupational exposure of the skin to beryllium compounds. Guinea pigs were sensitized to beryllium sulfate according to the maximized Magnusson and Kligman
Priyatham Gorjala et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 23(6), 1061-1073 (2010-06-16)
In fibroblasts, beryllium salt causes activation of the p53 transcription factor and induction of a senescence-like state. It is not known whether Be(2+) can affect the proliferation of cancer cells, which are generally unsusceptible to senescence. A172 glioblastoma and RKO
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