106577
2-Iodohippuric acid
98%
Synonym(s):
N-(2-Iodobenzoyl)glycine
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10 G
R$605.00
About This Item
Linear Formula:
IC6H4CONHCH2CO2H
CAS Number:
Molecular Weight:
305.07
Beilstein:
1877943
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
reaction suitability
reaction type: solution phase peptide synthesis
mp
170-172 °C (lit.)
SMILES string
OC(=O)CNC(=O)c1ccccc1I
InChI
1S/C9H8INO3/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)
InChI key
CORFWQGVBFFZHF-UHFFFAOYSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Yasushi Fujioka et al.
Bioconjugate chemistry, 16(6), 1610-1616 (2005-11-17)
Renal localization of radiolabeled antibody fragments presents a problem in targeted imaging and radiotherapy. We recently reported that Fab fragments labeled with 3'-[(131)I]iodohippuryl N(epsilon)-maleoyl-l-lysine (HML) demonstrated markedly low renal radioactivity levels from early postinjection in mice. Previous studies suggested that
Malgorzata Lipowska et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 53(8), 1277-1283 (2012-06-22)
In an ongoing effort to develop a renal tracer with pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mercaptoacetyltriglycine and (131)I-o-iodohippurate ((131)I-OIH), we evaluated a new renal tricarbonyl radiotracer based on the aspartic-N-monoacetic acid (ASMA) ligand, (99m)Tc(CO)(3)(ASMA).
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(4), 578-584 (2013-02-21)
The pharmacokinetics of the tricarbonyl core radiopharmaceutical (99m)Tc(CO)3-nitrilotriacetic acid ((99m)Tc(CO)3(NTA)) in rats and subjects with normal renal function are comparable to those of (131)I-o-iodohippuran ((131)I-OIH), the radiopharmaceutical gold standard for the measurement of effective renal plasma flow. Our objective was
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 45(5), 885-891 (2004-05-12)
99mTc-Mercaptoacetyltriglycine ((99m)Tc-MAG3) and (99m)Tc-L,L-ethylenedicysteine ((99m)Tc-LL-EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances less than that of (131)I-orthoiodohippurate ((131)I-OIH), and (99m)Tc-LL-EC exists in dianionic and monoanionic forms at physiologic pH. In an effort to develop a superior (99m)Tc
W M Michels et al.
Clinical nephrology, 72(5), 337-343 (2009-10-30)
Measuring GFR using exogenous markers without a bladder catheter, errors can be easily made due to incomplete urine collection. The aim was to quantify agreement for 125I-iothalamate GFR measurements with and without a correction for inaccurate urine collection using 131I-hippuran.
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