M1650000

Methyl parahydroxybenzoate

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): Methyl 4-hydroxybenzoate, p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN
• Linear Formula: HOC₆H₄CO₂CH₃
• CAS Number: 99-76-3
• Molecular Weight: 152.15
• Beilstein: 509801
• MDL number: MFCD00002352
• UNSPSC Code: 41116107
• PubChem Substance ID: 329817698
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: parabens
• manufacturer/tradename: EDQM
• mp: 125-128 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: COC(=O)c1ccc(O)cc1
• InChI: 1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
• InChI key: LXCFILQKKLGQFO-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for use according to European Pharmacopoeia for the preparation of the below-given solutions:

• Reference solutions (a) and (b) in the identification, testing for related substances, and assay of methyl parahydroxybenzoate and sodium methyl parahydroxybenzoate, according to the monographs 0409 and 1262
• Reference solution (c) for the testing of related substances in nifuroxazide using liquid chromatography (2.2.29), according to the monograph 1999
• Reference solution (b) in the identification of sodium ethyl parahydroxybenzoate using thin-layer chromatography (General text 2.2.27), according to the monograph 2134

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS09
• Hazard Statements: H411
• Precautionary Statements: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): 334.4 °F
• Flash Point(C): 168 °C